Association of the Vitamin D Metabolism Gene CYP27B1 With Type 1 Diabetes
نویسندگان
چکیده
منابع مشابه
Association of the vitamin D metabolism gene CYP27B1 with type 1 diabetes.
OBJECTIVE Epidemiological studies have linked vitamin D deficiency with the susceptibility to type 1 diabetes. Higher levels of the active metabolite 1 alpha,25-dihydroxyvitamin D (1 alpha,25(OH)(2)D) could protect from immune destruction of the pancreatic beta-cells. 1 alpha,25(OH)(2)D is derived from its precursor 25-hydroxyvitamin D by the enzyme 1 alpha-hydroxylase encoded by the CYP27B1 ge...
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ژورنال
عنوان ژورنال: Diabetes
سال: 2007
ISSN: 0012-1797,1939-327X
DOI: 10.2337/db07-0652